PARTNER 8
Imperial College London
Prof. Paul French

Address:
Department of Physics - South Kensington Campus – London SW7 2AZ

Telephone: +44 (0)207 594 7755

Fax: +44 (0)207 594 7714

Webpage: www.imperial.ac.uk/research/photonics/

Members

Name	Email	Telephone
Paul French	paul.french@imperial.ac.uk	+44 2075947706
Mark Neil	mark.neil@imperial.ac.uk	+44 2075947611
Egidius Auksorius	e.auksorius@imperial.ac.uk	+44 2075947745
Khadija Tahir	k.tahir@imperial.ac.uk	+44 2075947732
Raul del Coso	raul.delcoso@imperial.ac.uk	+44 2075947755

Main Research Activities

The Photonics Group of the Imperial College London is mainly working in the development and optimization of several microscopy devices and tools for in-vivo imaging of cells and sub-cellular structures. Collaborating with other partners of the project, we are developing and integrating an ultrafast fluorescence lifetime detection system, a new compact electronically tunable laser source and several advanced microscopical approaches (wide-field sectioning microscope, multiphoton imaging, hyperspectral detection…). This technological effort continues throughout the project and the multiparameter fluorescence lifetime microscopes are currently applied to solve biologically relevant problems. The novel fluorescence lifetime imaging tools make possible the dynamic determination of the location in cells of multiple molecules and of their immediate nanoscopic environment.

Most Relevant Publications

- “An electronically tunable ultrafast laser source applied to fluorescence imaging and fluorescence lifetime imaging microscopy” C. Dunsby, P.M.P. Lanigan, J. McGinty, D.S. Elson, J. Requejo-Isidro, I. Munro, N. Galletly, F. McCann, B. Treanor, B. Önfelt, D.M. Davis, M.A.A. Neil and P.M.W. French

J. Phys D: Appl. Phys., 37 3296-3303 (2004)

- “Time-resolved fluorescence anisotropy imaging applied to live cells”

Klaus Suhling, Jan Siegel, Peter M. P. Lanigan, Sandrine Lévêque-Fort, Stephen E. D. Webb, David Phillips, Daniel M. Davis, and Paul M. W. French

Opt Lett, 29 (2004) 584

- “Time-domain fluorescence lifetime imaging applied to biological tissue”

Dan Elson, Jose Requejo-Isidro, Ian Munro, Fred Reavell, Jan Siegel, Klaus Suhling, Paul Tadrous, Richard Benninger, Peter Lanigan, James McGinty, Clifford Talbot, Bebhinn Treanor, Stephen Webb, Ann Sandison, Andrew Wallace, Dan Davis, John Lever, Mark Neil, David Phillips, Gordon Stamp, and Paul French

Photochem. Photobiol. Sci., 3 (2004) 1-8

- “Biomedical Applications of Fluorescence Lifetime Imaging”

Dan Elson, Stephen Webb, Jan Siegel, Klaus Suhling, Dan Davis, John Lever, David Phillips, Andrew Wallace and Paul French,

Optics and Photonics News, 13 (2002) 27-32