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PARTNER 16-I Prof. Frank Grosveld |
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Address: 3000 DR The |
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Telephone: 0031 10 4087593 |
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Fax: 0031 10 4089468 |
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Email: f.grosveld@erasmusmc.nl |
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Webpage: www.eur.nl/fgg/ch1
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Members
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Name |
Email |
Telephone |
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N.
Galjart |
+31
104087173 |
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M.van
de Corput |
+31
104087315 |
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A.
Akhmanova |
+31
104638077 |
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W.
de Laat |
+31
104087164 |
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Main
Research Activities: Regulation of gene expression/hematopoietic development The cytoskeleton and intracellullar transport |
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Most
Relevant Publications Akhmanova, A.,
Hoogenraad, C., Drabek, K., Stepanova, T., Dortland, B., Verkerk, T., Burgering, B., de Zeeuw, C., Grosveld,
F. and Galjart, N. CLASPs are novel CLIP-115 and -170 associating proteins, which mark
microtubule ends at the leading edge of motile fibroblasts.
Cell, 23, 104(6):923-935, 2001. de Krom, M., van
de Corput, M., Grosveld, F. and Strouboulis, J. Stochastic patterns in globin
gene expression are established prior to
transcriptional activation and are clonally inherited.
Molecular Cell, 9(6):1319-26, 2002. Patrinos,
G., de Krom, M., de Boer, E., Langeveld, A., Strouboulis, J., Imam, A. and Grosveld, F. Multiple interactions
between regulatory regions are required to stabilise an Active
Chromatin Hub. Genes & Dev. 18(12):1495-509, 2004. Palstra, R.J.,
Tolhuis, B., Splinter, E., Nijmeijer, R., Grosveld, F. and De Laat, W. The
beta- globin nuclear compartment in development
and erythroid differentiation. Nat Genet. 35(2):190-4, 2003. Splinter,
E., Grosveld, F. and De Laat, W. 3C Technology: analyzing the spatial organisation of
genomic loci in vivo. Methods in
Enzymology, vol. 375, p.485-499,2004 |